TMJ Institute

Cranial Osteopathy was originated by the Osteopathic physician, William Garner Sutherland D.O. (1873-1954). His 54 year epic journey began when, during Divine Providence he notice too the cranial sutures of the temporal bones got “beveled similar to the gills of a fish” bringing about the ability for movement with the parietal bones, allowing for expansion and contraction. TMJ Institute

His conversations approximately this discovery amongst his mentor Dr. Andrew Stills, the founder of the osteopathic school in Missouri was supported. Both men believed the system was “designed to breath”. He identified this respiration movement the primary respiratory mechanism. This idea that the bones of the skull could move was contrary to contemporary anatomical belief, then and today by some scientist and medical practitioners. Dr. Sutherland was a deeply spiritual man and later on illustrated its origin as the Breath of Life from what i read in the Book of Genesis 2:7.

This was an acknowledgement of the critical drive as a as a fundamental aspect of osteopathic philosophy. There are three approaches that have evolved since Dr. William Garner Sutherland first began investigating the semi-closed hydraulic system of the cranial system, which is comprised of the spine, the skull and its cranial sutures, diaphragms, fascia of the body and movement of Cerebral spinal fluid (CSF) through the spinal cord. They are called the mechanical, functional and biodynamic models. TMJ Institute

Each refers to the amount of intervention of the practitioner. Dr. Sutherland s’ own journey moved from intervention of the mechanical model to the softness of the listening approach of the biodynamic model. My studies also began in the mechanical model which motions tests, and has moved to the biodynamic approach. Sutherland began to teach this work to other osteopaths from about the 1930s until his death in 1954. His work was at first largely rejected by the mainstream osteopathic profession. It challenged the closely held beliefs among practitioners.

Obviously, this happens throughout any discipline that is practiced on the planet. Great thought is often challenged by a more mediocre mind. Craniosacral Therapy comes under attack and even ridicule because at this time those who disbelief in its authenticity and value offer no scientific support for this powerful model of healing. I find this laughable. Dr. Rollin Becker, DO was one of Dr. Sutherland’s accomplished proteges. TMJ Institute

He gave up his standard model of Osteopathic practice after 20 years to spend his last 35 years of practice performing craniosacral therapy because of its efficacy! Dr. Sutherland practice it for 54 years! Dr. James Jealous, the leading proponent of the Biodynamic approach to this healing modality, has been practicing successfully for 45 years! Stop suffering from TMJ anymore. Get your TMJ Institute ebook and live your life again!

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Stakeholder Opinions: Traumatic Brain Injury Hormonal therapy generates optimism

There remains no approved pharmacological or cellular treatment to improve the outcome of survivors of traumatic brain injury (TBI). In the past two decades, understanding of the cellular and molecular mechanisms that occur after TBI has grown and a combination of novel therapeutic strategies and approved molecules are presently being examined in clinical trials.( http://www.bharatbook.com/detail.asp?id=135953&rt=Stakeholder-Opinions-Traumatic-Brain-Injury-Hormonal-therapy-generates-optimism.html )

Scope

*Analysis of the patient potential of traumatic brain injury across the seven major markets and several rest of world markets.
*Review of key unmet clinical needs in the treatment of traumatic brain injury and current pipeline treatments.
*Identification of key opportunities and threats facing developers of treatments for traumatic brain injury.
*Insight from six internationally recognized key opinion leaders in the field of spinal cord injuries.

Highlights

The incidence of hospitalized cases of TBI is estimated to be higher than the annual incidence of several medical conditions including some cancer types, epilepsy, HIV/AIDS, multiple sclerosis and spinal cord injury. Therefore, developers of efficacious treatments for TBI stand to benefit from a sizeable patient population.

Despite the high level of unmet need in the treatment of TBI, TBI research is under-funded. The current situation may stem from poor awareness of TBI, pessimism resulting from the relatively high attrition rate in the TBI pipeline and the perception that an efficacious pharmacological treatment for TBI is unattainable.

A sizeable proportion of the clinical candidates are under development as neuroprotective treatments for TBI. The inclusion of two progesterone receptor agonists in the current pipeline is indicative of the rising level of optimism regarding the neuroprotective potential of progesterone in TBI.

Reasons to Purchase

*Quantify the incidence of hospitalized cases of TBI across the seven major pharmaceutical markets and identify key clinical unmet needs.
*Assess the opportunities and threats facing developers in the traumatic brain injury market.
*Utilize pipeline product profiles to identify potential in-licensing opportunities.

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Summary

Motor neuron diseases (MNDs) are characterized by gradual and progressive degeneration and death of motor neurons. Normally, messages from nerve cells in the brain, or upper motor neurons, are transmitted to nerve cells in the brain stem and spinal cord, known as lower motor neurons, and from there to skeletal muscles. Upper motor neurons direct the lower motor neurons to produce movements such as walking or chewing. Lower motor neurons control movement in the arms, legs, chest, face, throat, and tongue. Currently, there is no
cure for MNDs.

Motor neuron diseases include: amyotrophic lateral sclerosis (ALS, Lou Gehrig’s disease), post-polio syndrome (PPS), primary lateral sclerosis (PLS), progressive muscular atrophy (PMA), pseudobulbar palsy (spastic), progressive bulbar palsy (spastic and flaccid), and spinal muscular atrophy (SMA).

However, currently only amyotrophic lateral sclerosis (ALS, Lou Gehrigs disease) and spinal muscular atrophy (SMA Type I) attract attention of various companies as potential targets for stem cell therapy.

Stem Cell Therapy Perspectives in Treating Motor Neuron Diseases: ALS and SMA pipeline contains 7 R & D products undergoing development by 6 companies, all from the USA. Out of 7 products one product is in Phase I/II, three are in Phase I clinical trials, and three products are in preclinical stage of development. Six products are undergoing development for ALS, and one for ALS and SMA. The majority of adult stem cells used for the treatment of ALS and SMA are autologous, only one stem cells-based product is allotransplant. Patients own bone marrow was source of adult stem cells in four products, patients own skin in one product, fetal spinal cord tissue in one product, and embryonic stem cells in one product. Motor neurons were differentiated for use in two products. If there are no major setbacks, including alarming adverse effects, Expects that this pipeline will progress relatively efficiently. Possible positive therapeutic effects of motor neuron cell-based products for the treatment of both ALS and SMA may be expected. When evaluating results of products in this pipeline, it is important to remember that alternative for patients is death, and any positive result will have enormous significance.

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Currently there is no effective therapeutic approach to reverse the brain damage caused by stroke because adult brain cells have limited ability for self-repair and spontaneous axonal regeneration.

At the first glance, the repair of human brain after stroke appears unrealistic as there is a loss of countless number of neurons and glial cells. The functional improvement after stroke requires neuro-restorative process that includes neurogenesis, angiogenesis and synaptic plasticity, or ability of the connection between two neurons to change its strength. Stem cell therapy has the potential to induce all three neuro-restorative processes and to facilitate functional recovery offering a new approach to regenerate damaged brain tissue in stroke patients.

However, in comparison to stem cell-based therapy for other indications, such as cardiac diseases, peripheral arterial disease, diabetes and even spinal cord injury, the number of preclinical research or clinical studies in patients with stroke is very limited. This is the reason that there is still uncertainty in selection of the best type of stem cells for cellular grafts in stroke, or understanding of mechanisms involved in functional recovery and structural reorganization of damaged brain.

When considering stem cell therapy for the treatment of stroke, it is important to remember that brain is a very complex structure containing a maze of various cells, neuronal extensions, electrical signals and chemical transmissions, presenting extremely difficult task for its regeneration and functional recovery.

To be efficient, stem cell-based therapies for stroke are expected to fulfill two goals: they have to provide better circulation in brain through angiogenesis or neoangiogenesis, and to regenerate lost brain tissue.

Stem Cell Therapy for Stroke report shows pipeline that contains only eight R & D products undergoing development by 11 companies. Out of eight products only one product is in Phase III clinical trials and for one product the Investigational New Drug (IND) application is approved. Further analysis reveals that this R & D pipeline is the most conservative when compared to stem cell therapeutic R & D pipelines for the treatment of cardiac diseases, peripheral arterial disease, diabetes and spinal cord injury.

The majority (87%) of stem cells used for the treatment of spinal cord injury are mesenchymal stem cells and mesenchymal-like stem cells, which are undifferentiated in 88% of those products. Autologus stem cells, obtained from patient’s own tissues are used only in 37% of all products and embryonic-derived stem cells were not used in any of products undergoing development for the treatment of stroke

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Sometimes a light touch is all you need. At least, that’s what proponents of craniosacral therapy believe. This relatively new type of massage, which has only been widely used in the alternative mainstream for about 30 years, works to alleviate problems associated primarily with pain and loss of function. It does this by applying very light pressure to evaluate and correct the body’s craniosacral system: connected to the brain and spinal cord.

While the people who seek out cranisosacral therapy are sometimes disabled individuals or parents of babies who have undergone some type of birth trauma, it is also recommended for people who suffer from migraines, tension, anxiety and other relatively minor disorders. People who have it often report a variety of benefits, including improved sleep, better mobility and increased energy.

Unlike many other alternative treatments, there is lots of anecdotal evidence that craniosacral therapy can work – at least in very disabled patients. However, there is very little scientific evidence to back that up. And whether it will help you to sleep better, or make your baby’s colic go away or feel better, is also still up for discussion.

How Does Craniosacral Therapy Work?

Also known as CST or cranial osteopathy, this therapy centers around a very light massage on the craniosacral area, working the spine and the head together to realign bones, allow the spinal fluid to flow unrestricted, and reduce pain. Like many alternative therapies it claims to help the body heal itself, and says that by doing so it can bolster our ability to fight disease and help treat a variety of problems associated with either dysfunction or pain.

While having someone play around with your brain and spinal cord may sound a bit dicey, the massage is actually completely non-invasive and quite relaxing, involving a cranial osteopath gently manipulating your skull as you lie on a massage table and try not to think of Frankenstein.

It all started thanks to one Dr William G. Sutherland, who believed that the bones in the skull were pliable, and that by gently moving them and touching the membranes, muscles and tissues surrounding the brain and spinal cord, other bodily functions could be fixed, enhanced and improved.

According to one massage website, “when blockages occur in spinal fluid, an inharmonious balance in the body can occur, resulting in muscle and joint strain, emotional disturbances, and the improper operation of the body’s organs and central nervous system”.

Sutherland died in 1954, but he began teaching his ideas in the 1930s, and established the Sutherland Cranial Teaching Foundation a year before his death. His work was carried further by John Upledger DO, who has even founded his own institute called the Upledger Institute.

Since then his methods have been expanded on, and while several big academic treatises have been published expanding the technique’s merits, others have claimed that there is little scientific evidence to back them up.

One reason that may be the case is because of the wide spectrum of ailments craniosacral therapy claims to be able to treat. They include everything from chronic fatigue to colic to scoliosis, and also include autism, learning difficulties and post-traumatic stress disorder.

Benefit to Babies

Craniosacral therapy has long been seen as a way to relieve minor problems in newborns and infants. It is thought that during delivery the head and muscles near the head may be traumatised, especially if there has been an aided birth using forceps or ventouse suction.

While there is no evidence that CST can help, no adverse effects have been reported and the vast majority of babies – and their parents – find the whole affair a calming, relaxing experience.

Reasons parents take their babies to a craniosacral therapist include:
Reflux/colic
Sleeping problems
Feeding problems
Inability to breastfeed properly
Excess crying
Asymmetrical head shape

Please note that if you decide to take your baby to a craniosacral therapist yo may be able to get help from your insurance company to pay for it, so get a referral before you go.

Helping Disabled People

CST can also be of benefit to people who have experienced severe medical problems, such as spinal cord injuries due to accident, cerebral palsy and other conditions. While proponents of it as a healing tool do not claim that it can cure problems, they hope that its less-invasive techniques can help patients develop their own muscle and nervous systems to protect themselves against further worsening of the condition, or other disease in general.

According to a craniosacral therapist who has worked with adults who have cerebral palsy for the last five years: “Many of these look forward to their CST sessions to relieve tight and twisted fascia that impedes the cerebral spinal fluid from circulating easily. Many report fewer headaches and backaches, less stress and more mobility. This often makes a significant difference in the quality of life for someone with disabilities.”

While insurance will probably not cover CST to treat CP, if the condition was a result of an accident at birth, your pay-out may be able to cover it.

Scientific or Silly?

CST is known as a gentle yet powerful treatment that has positive effects for many people. While it may not work for everyone – and while it doesn’t claim to be able to cure everything – the fact that it is non-invasive with no adverse effects means many people are willing to give it a go.

Before you break into your bank balance, however, keep in mind that this therapy – like most alternative and/or complementary treatments – has its critics. “I do not believe that craniosacral therapy has any therapeutic value. Its underlying theory is false because the bones of the skull fuse by the end of adolescence and no research has ever demonstrated that manual manipulation can move the individual cranial bones,” writes Dr Stephen Barrett MD in his Quackwatch website.

“Nor do I believe that ‘the rhythms of the craniosacral system can be felt as clearly as the rhythms of the cardiovascular and respiratory systems,’ as is claimed by another Upledger Institute brochure. The brain does pulsate, but this is exclusively related to the cardiovascular system, and no relationship between brain pulsation and general health has been demonstrated.”

As always, you be the judge…

The information in the article is not intended to substitute for the medical expertise and advice of your health care provider. We encourage you to discuss any decisions about treatment or care an appropriate health care provider.

Sarah Matthews is a writer for Yodle, a business directory and online advertising company. Find a therapist or more personal care articles at Yodle Consumer Guide. Craniosacral Therapy: Manipulating Your Brain and Spinal Cord



Stem Cell Therapy for Spinal Cord Injury report presents 12 R & D stem cell-based product profiles, 10 company profiles and investors information. This report emphasizes advantages and disadvantages of particular cell therapies for spinal cord injury, characteristics and origin of used cells, mechanism of their action, efficacy and adverse effects, mode of delivery, design of clinical trials and result of completed clinical studies.

When considering stem cell therapy, as the new avenue for the treatment of spinal cord injury, it is important to remember that spinal cord is a very complex structure containing a maze of various cells, neuronal extensions, electrical signals and chemical transmissions, presenting extremely difficult task for its regeneration and functional recovery. In addition, injured spinal cord represents one of the most hostile tissue environments for survival and therapeutic effect of transplanted stem and progenitor cells.

Analysis reveals that in the last two years research related to stem cell therapies for the treatment of spinal cord injury had abruptly and significantly shifted from mesenchymal and mesenchymal-like stem cells towards neural stem cells. However, in the commercial R & D pipeline, undergoing development by various companies, the majority (75%) of stem cells used for the treatment of spinal cord injury are mesenchymal stem cells and mesenchymal-like stem cells, which are undifferentiated in 55% of those products. Autologus stem cells, obtained from patient’s own tissues are used in 66%, embryonic-derived stem cells in 17% and allogenic stem cells in 17% of all stem cell transplantations for the treatment of spinal cord injury. Half of products are in preclinical stage of development and only one is in Phase II clinical trials. Out of 10 companies involved in research and development of stem cell-based therapies for spinal cord injury eight are from the USA, one is from Asia and one is from Europe. None of the major pharmaceutical or biotechnology companies are involved in development of stem cell products for the treatment of spinal cord injury.

In conclusion, this pipeline needs update with introduction of more adult neural stem cells-derived and embryonic stem cells-derived products and more investment by large pharmaceutical companies.

Expects that in the future profiles of stem cells used for the treatment of spinal cord injury will change from mesenchymal and mesenchymal-like stem cells and their progenitor to neural stem/progenitor cells. In addition, biodegradable scaffolds will be preferred mode of delivery of stem cells into injured spinal cord and surrounding tissue.

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stem cells spinal cord injury neural stem cell scaffold

Author: livestrong
Keywords: knee braces injuries physical therapy
Added: June 25, 2009



physical therapy for T4 vertebrae